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County Public Health Investigating Possible Local Spread of Clade I Mpox After Third Case Confirmed in Los Angeles County
- [登録者]Los Angeles County Public Health
- [言語]English
- [エリア]Los Angeles, CA, US
- 登録日 : 2025/10/17
- 掲載日 : 2025/10/17
- 変更日 : 2025/10/17
- 総閲覧数 : 181 人
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*For Immediate Release:*
October 17, 2025
*County Public Health Investigating Possible Local Spread of Clade I Mpox After Third Case Confirmed *
*in Los Angeles County*
"Third case also with no recent travel"
The Los Angeles County Department of Public Health is investigating the possibility of a local spread of Clade I mpox cases after confirming its second case in an adult with no recent travel to regions where this virus is typically found. The individual was hospitalized and is now recovering at home.
This is the third clade I mpox case in LA County and the third in the nation without known travel to another country where clade I is typically found. Public Health announced [ http://ph.lacounty.gov/phcommon/public/media/mediapubhpdetail.cfm?prid=5160&utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] its first case yesterday and, earlier this week, the City of Long Beach, which has its own health department, announced [ https://longbeach.gov/press-releases/city-of-long-beach-confirms-first-case-of-clade-i-mpox/?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] its first case. At this time, no clear link has been identified between the cases.
Public Health continues collaborating closely with California Department of Public Health and the U.S. Centers for Disease Control and Prevention (CDC) to investigate these mpox cases as swiftly and effectively as possible. Enhanced surveillance and contact tracing are underway to identify any additional cases and potential sources of the infection and to prevent further transmission. The CDC is conducting additional testing to identify the virus’s genes (genomic sequencing) in each case.
*How Mpox Clade I and Clade II Differ*
Mpox is caused by two main types or clades of the mpox virus: clade I and clade II.
* Clade II causes mild to moderate illness and has been circulating at low levels in the United States since 2022.
* Clade I may be more severe than clade II and has recently been linked to outbreaks in some African countries since 2024.
Both clade I and clade II may present with flu-like symptoms followed by a rash and can be spread through close person contact (sex, massage or cuddling) and within households or by sharing personal items. Laboratory testing of lesions can confirm a diagnosis for clade I and clade II mpox.
So far in 2025, Public Health has reported 118 [ https://app.powerbigov.us/view?r=eyJrIjoiNGI5MmEyMmQtYzVjMS00OTgwLWFhMDgtM2YyMTkxMjJlNmFhIiwidCI6IjA3NTk3MjQ4LWVhMzgtNDUxYi04YWJlLWE2MzhlZGRiYWM4MSJ9&utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] cases of clade II mpox.
"The confirmation of a third case with no travel history raises concerns about possible local spread in Los Angeles County," said Muntu Davis, MD, MPH, Los Angeles County Health Officer. "We’re working closely with our partners to identify potential sources and understand how this potentially more serious type of the mpox virus may be spreading."
*Public Health strongly recommends*:
* *Get Vaccinated.* Vaccination with both doses remains an effective tool in preventing the spread of mpox. The JYNNEOS vaccine is a safe, two-dose vaccine that helps protect against both clade I and clade II mpox, and getting both doses provides the best protection.
The vaccine is available for:
* Gay, bisexual, or other men who has sex with men;
* Transgender, nonbinary, or gender-diverse individuals;
* People with HIV or taking/eligible for HIV pre-exposure prophylaxis (PrEP) or doxy post-exposure prophylaxis (PEP) [ https://www.cdph.ca.gov/Programs/CID/DCDC/Pages/STI/DoxyPEP.aspx?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ];
* Anyone exposed to someone with mpox in the last 14 days;
* Anyone planning travel to sub-Saharan Africa or areas with clade I mpox outbreak [ https://www.cdc.gov/monkeypox/outbreaks/2023/index.html?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ]_s_ and anticipates sexual or intimate contact while traveling;
* Anyone planning to attend a commercial sex event or venue (like a sex club or bathhouse);
* Individuals with a sex partner who meets any of the above risk factors; or
* Anyone who requests mpox vaccination, even if they have not disclosed any risks factors listed above.
Additionally, the mpox vaccine is recommended for anyone at occupational risk for exposure to mpox [ https://www.cdc.gov/mmwr/volumes/71/wr/mm7122e1.htm?s_cid=mm7122e1_w&utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ](e.g., certain laboratory workers).
People in high-risk groups are urged to get fully vaccinated. Second doses can be given no matter how long it’s been since the first dose. Vaccine boosters (i.e., third doses) are not recommended at this time.
Pharmacies across LA County offer the vaccine. To locate a nearby pharmacy location with JYNNEOS vaccine, visit the Bavarian Nordic Vaccine Locator [ https://empoweredagainstmpox.com/?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term=#locator-map ] webpage. Individuals can also call their healthcare providers to inquire about receiving JYNNEOS. Public Health also maintains a list of public vaccination sites [ http://publichealth.lacounty.gov/ip/Docs/PublicMpoxReferral.pdf?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] that carry the JYNNEOS vaccine which is updated frequently. Most health insurance plans should cover JYNNEOS vaccine for eligible individuals; this includes Medi-Cal, Medicare, and private insurance. Residents are advised to contact their health plan to find out if they cover JYNNEOS. People should call ahead to make sure the JYNNEOS vaccine is available in advance of going to a vaccine provider.
For uninsured and underinsured individuals, JYNNEOS vaccine is a covered service for eligible persons enrolled in the PrEP Assistance Program (PrEP-AP) [ https://www.cdph.ca.gov/Programs/CID/DOA/Pages/PrEP-AP.aspx?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] or AIDS Drug Assistance Program (ADAP) [ https://www.cdph.ca.gov/Programs/CID/DOA/pages/oaadap.aspx?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ]. Uninsured and underinsured individuals can also access free JYNNEOS vaccine at Public Health Sexual Health Clinics [ http://publichealth.lacounty.gov/chs/sexualhealthclinics/?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ]. Appointments and visits as soon as possible are strongly recommended to ensure availability of the limited supply of vaccine. Public Health’s sexual health clinics found at http://publichealth.lacounty.gov/chs/sexualhealthclinics/ [ https://lnks.gd/l/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.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.O_8JXMGBRovsqudvIdFYPaicFy1N4DHvRwPQYEBHxxY/s/2971352109/br/249632645336-l?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ]
For more information on how to get the mpox JYNNEOS vaccine, call the Public Health Infoline at 1-833-540-0473, seven days a week, 8 a.m. – 8 p.m.
* *Get Tested if You Have Symptoms.* Symptoms consistent with mpox include rash, fever or swollen lymph nodes. If symptoms develop, seek medical attention and get tested.
Health care providers should be aware of the possibility of mpox and promptly test suspected cases. Providers should immediately notify Public Health if the patient has traveled to Africa in the past 21 days to facilitate expedited testing.
* *Practice Prevention.* Reduce the risk of getting and spreading mpox by:
* Not having sex or close contact if you or your partner(s) have mpox symptoms, such as a new or unexplained rash or sores or feels sick until they see a health care provider.
* Reducing the number of sexual or close contact partners, especially if their recent sexual history is unknown.
* Making a habit of exchanging contact info with any new partner for sexual health follow-up if needed.
* Limiting going to sex or circuit parties or spaces with intimate contact with multiple people.
* Using condoms and gloves during sexual activity:
* Condoms (latex or polyurethane) may protect the mouth, penis anus or vagina from exposure to mpox; however, condoms alone may not prevent all exposures to mpox since the rash can occur on other parts of the body.
* Gloves (latex, polyurethane or nitrile) may reduce exposure if inserting fingers or hands into the anus or the vagina. The gloves must cover all exposed skin and be removed carefully to avoid touching the outer surface.
* Not sharing towels, clothing, bedding, fetish gear, sex toys or toothbrushes.
* Washing hands and all gear, towels, bedding and sex toys thoroughly after use or sex act.
For the most up-to-date information and resources, please visit ph.lacounty.gov/mpox [ http://publichealth.lacounty.gov/media/monkeypox/?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ] or contact the Public Health Info Line at 1-833-540-0473, seven days a week, 8 a.m. – 8p.m.
*About Mpox*
Mpox (previously referred to as Monkeypox) is mainly spread through close contact with body fluids, sores, shared bedding or clothing or respiratory droplets (kissing, coughing, sneezing). Symptoms include rash or unusual sores that look like pimples or pus-filled blisters on the face, body and genitals, fever, chills, headache, muscle aches or swelling of lymph nodes. Early detection, testing and vaccination are vital to controlling the spread of this disease and protecting the health of Los Angeles County residents. For more information visit our website [ http://publichealth.lacounty.gov/media/monkeypox/?utm_content=&utm_medium=email&utm_name=&utm_source=govdelivery&utm_term= ].
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